Chronic myeloid leukemia (CML) is the least common type of pediatric leukemia (accounts for only 1% or so).
CML is rare in children but more prevalent in adults.
The incidence is about 1 per 100,000 in people less than 20 years old.
- Most frequent variant of myeloproliferative disorders
- Adult CML variant appears in children >4 years old
- >80% of cases diagnosed after 4 years old
- 60% of cases diagnosed after 6 years old
Frequency of Chronic Myeloid Leukemia in Children:
Peak Incidence Median Age |
Early adolescent 12 years of age |
Racial Bias |
More common in Caucasian than African-American |
Gender Bias |
Male>Female (slightly) |
External Links:
Chronic Myeloid Leukemia at the Atlas of Genetics and Cytogenetics in Haematology and Oncology