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Chronic Myeloid Leukemia






Chronic myeloid leukemia (CML) is the least common type of pediatric leukemia (accounts for only 1% or so). 

CML is rare in children but more prevalent in adults.

The incidence is about 1 per 100,000 in people less than 20 years old.

  • Most frequent variant of myeloproliferative disorders
  • Adult CML variant appears in children >4 years old
  • >80% of cases diagnosed after 4 years old
  • 60% of cases diagnosed after 6 years old


Frequency of Chronic Myeloid Leukemia in Children:

Peak Incidence

Median Age

Early adolescent

12 years of age

Racial Bias

More common in Caucasian than African-American

Gender Bias

Male>Female (slightly)



External Links:

Chronic Myeloid Leukemia at the Atlas of Genetics and Cytogenetics in Haematology and Oncology

Chronic Myeloid Leukemia at the National Cancer Institute

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