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Acute Lymphoblastic Leukemia






ALL is biologically heterogeneous.

May develop at any point during the multiple stages of normal lymphoid differentiation.

ALL is classified in several ways:

  • Morphology - appearance
  • Immunologic characteristics - cell surface protein markers
  • Cytogenetic and molecular characteristics - genetic mutations
  • Cytochemical (biochemical) features - staining


The large purple cells below are ALL blast cells:





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