The management of this tumor is multidisciplinary and involves:
- Initial surgery
- Chemotherapy
- Radiation therapy (RT) - depending on the age of the patient
COG-ACNS0332: This is a COG phase III trial for children older than 3 years with high risk medulloblastoma or supratentorial PNET. The trial is evaluating the efficacy of adding carboplatin to radiation therapy with vincristine, followed by maintenance chemotherapy with conventional adjuvant chemotherapy and isotretinoin.
