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Supratentorial PNET

 

 

Introduction

Primitive NeuroEctodermal Tumors (PNET) are:

  • Derived from neuroepithelial stem cells (cells that are arrested in various stages of differentiation)15 

 

Central nervous system PNETs are classified by their location relative to the tentorium20:

Infratentorial:

  • Tumors arising below (infra) the tentorium
  • Called medulloblastomas

Supratentorial:

  • Tumors arising above (supra) the tentorium
  • Called Supratentorial PNETs

 

Type of PNET

Location

Incidence of PNET

Infratentorial (medulloblastoma)

Cerebellum

>90%

Supratentorial

Above tentorium

<10%

 

In the following diagram, S points to the supratentorial brain, T points to the tentorium and I points to the infratentorial brain or cerebellum.

 

Wikipedia: Tentorium cerebelli

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