- Not a good method for evaluating response as resolution is slow.
Below is a bone scan which shows a metastatic deposit in the upper lumbar spine (#1) from OS.
- Gives very useful staging information.
- Possible use in response evaluation. Thallium has been used in past for correlation with histologic response but has been largely replace by PET.
Below is a CT/PET scan of a metastatic deposit from OS involving a vertebral body. #1 shows the bright yellow area of increased FDG uptake.
Below is a PET showing transverse, sagittal and coronal (whole body) views of a patient with OS. The red circle shows where there is avid uptake in the region of the primary tumor. There is no evidence of distant metastatic disease.