The differential diagnosis of a renal tumor includes benign processes as well as malignancies.
Neuroblastoma is the most common differential diagnosis of Wilms tumor.
Features that distinguish between Wilms tumor and Neuroblastoma:
Wilms Tumor |
Neuroblastoma |
|
Abdominal mass |
Yes |
Yes |
Primary origin |
Intrarenal |
Extrarenal |
Physical examination |
Displacing mass, mainly confined to the flank |
Non-mobile mass. more likely to cross the midline |
Pattern of tumor spread |
Direct expansion with displacement of adjacent structures |
Encasement of vessels and aortic elevation |
Other |
Intrinsically displaces urinary collecting systems |
Externally displaces kidney Often calcified |
- In addition to neuroblastoma, other neoplasms are sometimes confused with Wilms tumor based on similar clinical presentations.
- There are benign and malignant causes of an abdominal mass.
Differential diagnoses of a Renal Mass:
| Benign | Malignant |
Multicystic kidneys Renal abscess |
Renal rhabdoid tumor Fibrosarcoma Malignant neurogenic tumor
|
