Non-RMS generally present as an increasing, painless mass.
Rarely associated with any warmth, erythema (redness) or tenderness.
Common sites include:
- Extremity
- Trunk
- Posterior thorax
- Flank
- Abdominal wall
It is possible for these tumors to arise intra-abdominally, but this is very rare in children.
Pain only occurs when there is invasion of adjacent neuro-vascular structures.
There is no evidence that trauma is a cause of non-RMS, though sometimes these tumors are only noticed after trauma.
The average time interval between the initial symptom and diagnosis is 2 months (interval longer in adolescents than very young children).
