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Bone Marrow Transplant



Transplant Process



Hematopoietic Stem Cell Transplantation (HSCT) is divided up into different phases:

  • Recipient evaluation
  • Conditioning / preparative regimen:
    • Delivers chemotherapy, radiation therapy (RT), or both to eliminate malignancy, prevent rejection of new stem cells, and create space for the new cells
  • Transplant itself:
    • Stem cell infusion
  • Aplastic phase:
    • The patient has no effective immune system and the bone marrow is not functioning.  This lasts for roughly 2-4 weeks.
    • Engraftment phase is when the new bone marrow starts to function and acute graft versus host disease is seen at this time
  • Long-term follow-up phase:
    • This is the "post-engraftment" phase and lasts many months to years after the transplant







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