Pediatric Leukemias are classified in several ways
- Morphology - appearance
- Cytochemical features - staining
- Immunologic characteristics - cell surface protein markers
- Cytogenetic and molecular characteristics - genetic mutations
Onset / Course |
Acute vs Chronic |
Cell lineage |
Myeloid vs Lymphoid |
T cell vs B cell (ALL) | |
FAB classification | |
WHO classification (AML) |
Acute
- “Sudden” onset
- Death in weeks to months if untreated.
Chronic
- Insidious onset
- Death in years if untreated
- Rare in pediatrics