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Differential Diagnosis



Abdominal mass

Differential Diagnosis of an abdominal mass:

Congenital vs Acquired

Hydronephrosis Rarely causes mass like abdominal swelling


Polycystic disease Mass like swelling
Congenital gut duplications Rare


Non-infectious Renal Vein Thrombosis
Traumatic Injury Adrenal hemorrhage can cause adrenal calcification.



Wilms Tumor:

  • More likely to have a large unilateral flank mass
  • Less likely to cross the midline
  • Less likely to be calcified
  • Almost always present with signs and symptoms of primary tumor mass



  • More likely to present with signs and symptoms of metastatic disease than Wilms tumor
  • May present with abdominal pain and a palpable mass
  • More likely to be calcified and cross the midline than Wilms tumor


  • More likely to have systemic symptoms such as fever, night sweats
  • Less likely to cause a large abdominal mass.


  • Often presents with large abdominal mass

Adrenal Carcinoma:

  • Very rare in children

Renal Cell Carcinoma:

  • Very rare in children

Rhabdomyosarcoma (RMS):

  • May present with an abdominal mass.

Other non-RMS sarcomas such as fibrosarcoma:

  • Very rare




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