RMS can occur anywhere (but usually in or near striated muscle).
The presentation will depend on where the disease starts.
Usually a mass appears in a body region with no history of trauma, or organ function is compromised by tumor growth.
Presenting Signs & Symptoms of RMS arising in different sites:
Location |
Relative frequency |
Signs and symptoms |
Head and neck:
|
40%
|
|
Genitourinary tract:
|
29%
|
|
Extremities |
14% |
|
Trunk |
12% |
|