Respiratory
Disease
Tumour Related Lung Disease
Langerhans cell histiocytosis (LCH) is a disease of unknown etiology which may affect a number of organs including the lung39.
There is a known association between LCH and smoking
The natural history of pulmonary LCH varies from spontaneous remission to progressive respiratory insufficiency and death.
Poor prognostic factors include:
- Pneumothorax
- Multisystem disease
- Extensive pulmonary involvement with cyst formation and impaired diffusing capacity
Monitoring - Pulmonary status should be monitored with PFTs and if necessary high resolution CT scan.
