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Ophthalmology for the Oncologist

 

 

Reduced vision

 

Reduced vision can be due to:

Table : Summary of the causes of reduced vision in oncology patients

Keratitis 

Cataract   

Uveitis   

Retinal   disease

Optic nerve disease

Visual Pathway disease

 

Keratitis

Can present with visual loss and:

  • red eye
  • photophobia
  • pain

Investigated with fluorescein staining

Causes:

  • bacterial keratitis
  • HSV dendritic ulcer
  • dry-eye related.

 

Cataract   

Can present with visual loss and:

  • painless
  • impaired red reflex

Investigated with direct ophthalmoscopy

Causes:

  • steroids
  • radiation
  • intraocular tumour
  • Busulphan

 

Uveitis        

Can present with visual loss and:

  • circumcorneal redness
  • photophobia
  • pain

Causes:

  • infective
  • leukaemic infiltration

 

Retinal   Disease

Can present with visual loss and:

  • Painless (Acute / Chronic)

Causes:

  • Infective
  • Leukemic infiltration
  • Drugs (cisplatin, etoposide)

 

Optic nerve Disease

Can present with visual loss and:

  • painless (Acute / Chronic)
  • poor pupil response

Causes:

  • leukemic infiltration
  • optic nerve tumours (gliomas / meningiomas)
  • radiation
  • drugs (eg. vincristine)

 

  Visual Pathways Disease   (especially chiasm / optic nerve lesions)

Due to

  • Intracranial tumour
  • Intracranial infection

 Below is a picture of bilateral posterior subcapsular cataracts secondary to prolonged systemic steroids

 

 

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